Lawrence Livermore National Laboratory

For more than 60 years, the Lawrence Livermore National Laboratory has applied science and technology to make the world a safer place.

Livermore’s defining responsibility is ensuring the safety, security and reliability of the nation’s nuclear deterrent. Yet LLNL’s mission is broader than stockpile stewardship, as dangers ranging from nuclear proliferation and terrorism to energy shortages and climate change threaten national security and global stability. The Laboratory’s science and engineering are being applied to achieve breakthroughs for counterterrorism and nonproliferation, defense and intelligence, energy and environmental security.

For a general overview of Lawrence Livermore National Laboratory, including its core capabilities, visit LLNL's Solution Center profile or their home page. Learn more about individual user facilities below. 

Advanced Manufacturing Laboratory (AML)

Located in the heart of the Livermore Valley Open Campus and adjacent to LLNL’s main campus, the AML will be the birthplace of tomorrow’s most innovative manufacturing processes and products. The facility is actively searching for strategic partners to help make this vision a reality.

The AML will house the most advanced and capable equipment in the field of advanced/additive manufacturing, some of which are not yet commercially available. Additional resources will include material evaluation and characterization equipment, high-performance computing (HPC) modeling and simulation systems, and manufacturing capabilities from several active LLNL programs. Advances made at the AML will be accelerated through a motivation of dual-purpose applications—both commercial and government products. AML strategic partners will enjoy research and development benefits via forward-thinking agreements tailored to each party’s needs. The facility's goals:

  • Ensure exclusive space allocation
  • Define equipment use
  • Preserve industry intellectual property ownership
  • Respect confidentiality

AML's mutually beneficial partnership strategy is driven by a concept known as Spin-Out/Spin-In. Technology developed at the AML “spins-out” for commercial application and development, while also offering the opportunity for LLNL to “spin-in” commercially developed products or processes. The process also works in the other direction: The commercial partner’s technology is enhanced with LLNL advancements and expertise, after which it is adapted to the partner’s products.

For more information, please visit the AML website.

Center for Accelerator Mass Spectrometry (CAMS)

The Center for Accelerator Mass Spectrometry (CAMS) is a signature facility of LLNL that uses diverse analytical techniques and state of the art instrumentation, to develop and apply unique, ultra-sensitive isotope ratio measurement and ion beam analytical techniques to address a broad spectrum of scientific needs important to the Laboratory and the nation. CAMS hosts a 10-MV FN tandem Van de Graaff accelerator, a NEC 1-MV tandem accelerator and a soon to be commissioned 250KV single stage AMS deck to perform up to 25,000 AMS measurement per year, as well as a NEC 1.7-MV tandem accelerator for ion beam analysis and microscopy. CAMS activities have broad ranging scientific impact while contributing to LLNL mission needs.

CAMS has the following Isotope ratio competencies:

  • Forensics
  • Public Health
  • Carbon Cycle
  • Climate Change/Paleoclimate & Geochronology
  • Atmospheric Chemistry
  • Earth System Processes
  • Environmental Radiochemistry
  • Dose Assessment and RadioEcology

And the following Ion beam competencies:

  • Radiation Damage/Materials Modification
  • Nuclear Science/Nuclear Chemistry

AMS sample analysis costs typically range from $50 to $1000 a sample dependent on isotope to be measured and sample preparation that may be required. Ion beam analysis capabilities on a fee-for-service basis are also available upon request.

For more information, please visit the CAMS website or contact:

Graham Bench

Jupiter Laser Facility (JLF)

The Jupiter Laser Facility (JLF) is a unique laser user facility for research in High Energy Density science. Its three diverse laser platforms offer researchers a wide range of capabilities to produce and explore states of matter under extreme conditions of high density, pressure, and temperature. Titan is a dual-beam platform with a nanosecond, kJ long-pulse beam and a femtosecond, petawatt short-pulse beam derived from a neodymium-glass laser system. Janus is also based on the same neodymium-glass laser system but configured for operation with two nanosecond, kJ beams. COMET is a neodymium-glass laser system designed for the generation of laboratory X-ray lasers. You may submit a proposal for laser time.

The Jupiter Laser Facility (JLF) User Program is open to all qualified applicants; US and non-US PIs are welcome to submit proposals. Using technical evaluations from experts both in and outside LLNL, proposals will be reviewed and ranked by the JLF advisory committee based on scientific and/or programmatic quality, impact, and feasibility. Typically, platforms are over-requested by a factor of two or more.

For more information, please visit the JLF website.

National Ignition Facility (NIF)

The National Ignition Facility is the largest and most energetic laser facility ever built. NIF is the size of a sports stadium—three football fields could fit inside. NIF is also the most precise and reproducible laser as well as the world’s largest optical instrument. The giant laser has nearly 40,000 optics that precisely guide, reflect, amplify, and focus 192 laser beams onto a fusion target about the size of a pencil eraser. NIF became operational in March 2009.

For more information, please visit the NIF website.

The National Resource for Biomedical Accelerator Mass Spectrometry (BioAMS)

The National Resource for Biomedical Accelerator Mass Spectrometry (BioAMS) was established to make AMS available to biomedical researchers who need to accurately measure very low levels of 14C and other radioisotopes. The Resource is also working to enhance AMS for analysis of radioisotopes in biomedical tracer studies through development of new methods and instrumentation.

AMS is a technique for measuring isotope ratios with high selectivity, sensitivity, and precision. In general, AMS separates a rare radioisotope from stable isotopes and molecular ions of the same mass using a variety of standard nuclear physics techniques. Over the last 20 years, AMS has evolved as a biomedical tool, offering the required sensitivity, selectivity, and precision to address questions that alternative methodologies have been unable to achieve in practice.

The National Resource features a National Electrostatics Corporation 250kV accelerator mass spectrometer in our biomedical laboratory with the following capabilities:

  • HPLC separation, including a Waters Acquity UPLC system and a Waters Alliance HPLC system.
  • Radioisotope labeling of cells in our cell culture lab.
  • Screening of samples that potentially have too much 14C for AMS quantitation, using a Perkin Elmer Tri-Carb 2910TR liquid scintillation counter.
  • Conversion of radiocarbon-tagged biologicals to filamentous graphite in our dedicated graphite laboratory.

To utilize the BioAMS Resource, investigators should first discuss their interest with the staff of the Resource.

For more information, please visit the BioAMS website or contact:

Bruce Buchholz
(925) 422-1739